The 1943 Clare Senior Hurling Championship was the 48th staging of the Clare Senior Hurling Championship since its establishment by the Clare County Board in 1887.
Clooney entered the championship as the defending champions.
The final was played on 3 October 1943 at Cusack Park in Ennis, between Clarecastle and Scariff in what was their first ever meeting in the final. Clarecastle won the match by 4âÂÂ03 to 4âÂÂ02 to claim their first ever championship title.