There were elections in 1941, in the months leading up to World War II, to the United States House of Representatives:
|- ! | Kenneth F. Simpson | | 1940 | | Incumbent died January 25, 1941.<br/>New member elected March 11, 1941.<br/>Republican hold. | nowrap |
|- ! | Sam C. Massingale | | 1934 | | Incumbent died January 17, 1941.<br/>New member elected April 1, 1941.<br/>Democratic hold. | nowrap |
|- ! | Colgate Darden | | 1938 | | Incumbent resigned March 1, 1941, to run for Governor of Virginia.<br/>New member elected April 8, 1941.<br/>Democratic hold. | nowrap |
|- ! | Pius Schwert | | 1938 | |Incumbent died March 11, 1941.<br/>New member elected April 22, 1941.<br/>Republican gain. | nowrap |
|- ! | William D. Byron | | 1938 | | Incumbent died February 27, 1941.<br/>New member elected May 27, 1941.<br/>Democratic hold. | nowrap |
|- ! | Alonzo D. Folger | | 1938 | | Incumbent died April 30, 1941.<br/>New member elected June 14, 1941.<br/>Democratic hold. | nowrap |
|- ! | Walter W. Bankhead | | 1940 | | Incumbent resigned February 1, 1941.<br/>New member elected June 24, 1941.<br/>Democratic hold. | nowrap |
|- ! | Morris M. Edelstein | | 1940 <small>(special)</small> | | Incumbent died June 4, 1941.<br/>New member elected July 29, 1941.<br/>Democratic hold. | nowrap |
|- ! | Stephen Bolles | | 1938 | | Incumbent died July 8, 1941.<br/>New member elected August 29, 1941.<br/>Republican hold. | nowrap |
|- ! | Wall Doxey | | 1928 | | Incumbent resigned September 28, 1941, after being elected to the U.S. Senate.<br/>New member elected November 4, 1941.<br/>Democratic hold. | nowrap |
|- ! | Albert G. Rutherford | | 1936 | | Incumbent died August 10, 1941.<br/>New member elected November 4, 1941.<br/>Republican hold. | nowrap |
|- ! | Edward T. Taylor | | 1914 | | Incumbent died September 3, 1941.<br/>New member elected December 9, 1941.<br/>Republican gain. | nowrap |
|- ! | Lawrence J. Connery | | 1937 | | Incumbent died October 19, 1941.<br/>New member elected December 30, 1941.<br/>Democratic hold. | nowrap |