A presidential election was held in Indiana on November 5, 1940, as part of the 1940 United States presidential election. The Republican ticket of the president of the Commonwealth & Southern Corporation Wendell Willkie and the senior U.S. senator from Oregon Charles L. McNary defeated the Democratic ticket of the incumbent president of the United States Franklin D. Roosevelt and the U.S. secretary of agriculture Henry A. Wallace. Roosevelt defeated Willkie in the national election with 449 electoral votes.