The 1922 Oklahoma Sooners football team represented the University of Oklahoma as a member of the Missouri Valley Conference (MVC) during the 1922 college football season. In their 18th season under head coach Bennie Owen, the Sooners compiled an overall record of 2âÂÂ3âÂÂ3 record with a mark of 1âÂÂ2âÂÂ2 in conference play, placing sixth in the MVC, and were outscored by opponents by a combined total of 114 to 66.
No Sooners were recognized as All-Americans, and end Howard Marsh was the only Sooner to receive all-conference honors.