The 1918 United States House of Representatives elections in South Carolina were held on November 5, 1918, to select seven Representatives for two-year terms from the state of South Carolina. The primary elections were held on August 27 and the runoff elections were held two weeks later on September 10. All seven incumbents were re-elected and the composition of the state delegation remained solely Democratic.
Incumbent Democratic Congressman Richard S. Whaley of the 1st congressional district, in office since 1913, was unopposed in his bid for re-election.
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Incumbent Democratic Congressman James F. Byrnes of the 2nd congressional district, in office since 1911, won the Democratic primary and was unopposed in the general election.
|- | | colspan=5 |Democratic hold |-
Incumbent Democratic Congressman Frederick H. Dominick of the 3rd congressional district, in office since 1917, defeated Wyatt Aiken in the Democratic primary and was unopposed in the general election.
|- | | colspan=5 |Democratic hold |-
Incumbent Democratic Congressman Samuel J. Nicholls of the 4th congressional district, in office since 1915, won the Democratic primary and was unopposed in the general election.
|- | | colspan=5 |Democratic hold |-
Incumbent Democratic Congressman William F. Stevenson of the 5th congressional district, in office since 1917, was unopposed in his bid for re-election.
|- | | colspan=5 |Democratic hold |-
Incumbent Democratic Congressman J. Willard Ragsdale of the 6th congressional district, in office since 1913, was unopposed in his bid for re-election.
|- | | colspan=5 |Democratic hold |-
Incumbent Democratic Congressman Asbury Francis Lever of the 7th congressional district, in office since 1901, won the Democratic primary and defeated Republican R.H. Richardson in the general election.
|- | | colspan=5 |Democratic hold |-