The 1906 Latrobe Athletic Association season was their eleventh season in existence. The team finished 3âÂÂ1.
Latrobe's Thanksgiving loss against Canton (the team that would become the Canton Bulldogs of the National Football League in 1920) was the first Latrobe loss since 1901 and its first points allowed since 1903. The game may have motivated the Canton Bulldogs-Massillon Tigers betting scandal.