The 1828 Boston mayoral election saw the election of Harrison Gray Otis. The election required three votes, because no candidate secured the required majority in the first two votes. After failing in the first two votes, incumbent mayor Josiah Quincy III declined to run in the third round.
Running in the second round were Josiah Quincy III, Thomas C. Amory, Harrison Gray Otis, and Charles Wells.
Quincy and Amory declined to run again in the third vote.
Receiving a majority of the vote, Otis was elected mayor.