The 1821 Alabama gubernatorial election was held on August 6, 1821, to elect the third governor of Alabama. Democratic-Republican candidate Israel Pickens defeated fellow Democratic-Republican candidate Henry H. Chambers with 57.43% of the vote.
During the election campaign, it was alleged that Pickens had defrauded a woman in North Carolina while acting as her lawyer in a suit in Pennsylvania; the claim was refuted by accounts in letters to the Cahawba Press and Alabama Intelligencer.