The enzyme 16ñ-hydroxyprogesterone dehydratase () catalyzes the chemical reaction
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 16ñ-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming). Other names in common use include hydroxyprogesterone dehydroxylase, 16ñ-hydroxyprogesterone dehydroxylase, 16ñ-dehydroxylase, and 16ñ-hydroxyprogesterone hydro-lyase.