Fortunio Liceti publishes ' which marks the beginning of studies into malformations of the embryo.
Fabio Colonna publishes ' in Rome, including two appendices, ' and ', where he argues that "tongue stones" are of organic origin, being shark teeth, glossopetrae.
Croatian mathematicianFausto Veranzio publishes Machinae novae, a book of mechanical and technological inventions, some of which are applicable to the solution of hydrological problems, and others concern the construction of water clocks, sundials, mills, presses, bridges and boats.