1-hydroxy-2-naphthoate 1,2-dioxygenase () is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are 1-hydroxy-2-naphthoic acid and oxygen. Its product is (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoic acid.
This enzyme participates in phenanthrene metabolism. It employs one cofactor, iron.
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O<sub>2</sub> as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O<sub>2</sub>. The systematic name of this enzyme class is 1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing). Other names in common use include 1-hydroxy-2-naphthoate dioxygenase, 1-hydroxy-2-naphthoate-degrading enzyme, and 1-hydroxy-2-naphthoic acid dioxygenase.