In enzymology, a 1-alkenylglycerophosphocholine O-acyltransferase () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are acyl-CoA and 1-alkenylglycerophosphocholine, whereas its two products are CoA and 1-alkenyl-2-acylglycerophosphocholine.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:1-alkenylglycerophosphocholine O-acyltransferase. This enzyme participates in ether lipid metabolism.