1-deoxy-11beta-hydroxypentalenate dehydrogenase (, 1-deoxy-11beta-hydroxypentalenic acid dehydrogenase, (gene), (gene name)) is an enzyme with systematic name 1-deoxy-11beta-hydroxypentalenate:NAD<sup>+</sup> oxidoreductase. This enzyme catalyses the following chemical reaction
This enzyme from the bacterium Streptomyces avermitilis participates in pentalenolactone biosynthesis.