1,3-propanediol dehydrogenase

In enzymology, a 1,3-propanediol dehydrogenase () is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are propane-1,3-diol and NAD⁺, whereas its 3 products are 3-hydroxypropanal, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is propane-1,3-diol:NAD⁺ 1-oxidoreductase. Other names in common use include 3-hydroxypropionaldehyde reductase, 1,3-PD:NAD⁺ oxidoreductase, 1,3-propanediol:NAD⁺ oxidoreductase, and 1,3-propanediol dehydrogenase. This enzyme participates in ether lipid metabolism as a step in glycerolipid biosynthesis.

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