.45 Calibre War is a lost 1929 American silent Western film directed by Leo D. Maloney and starring Don Coleman, Ben Corbett and Jeanette Loff.
Reed Lathrop returns to his old home, accompanied by his friend, "Toad" Hunter, to investigate a plot that forces ranchers to sell their properties for very low prices. Finding the ranchers demoralized, he organizes a vigilance committee and enlists the aid of the local circuit judge. Darnell, the owner of the saloon, and Blodgett, a local dealer in ranch property, are unmasked as the culprits. Soon a showdown takes place with the ranchers and the outlaws, ending with the criminals hauled off to prison.
With no holdings located in archives, .45 Calibre War is considered a lost film.