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(acyl-carrier-protein) phosphodiesterase

The enzyme [acyl-carrier-protein] phosphodiesterase (EC 3.1.4.14) catalyzes the reaction

holo-[acyl-carrier-protein] + HO 4-phosphopantetheine + apo-[acyl-carrier-protein]

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name is holo-[acyl-carrier-protein] 4-pantetheine-phosphohydrolase. Other names in common use include ACP hydrolyase, ACP phosphodiesterase, AcpH, and [acyl-carrier-protein] 4-pantetheine-phosphohydrolase. This enzyme participates in pantothenate and CoA biosynthesis.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .

References