(S)-ò-bisabolene synthase (EC 4.2.3.55) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((S)-ò-bisabolene-forming). This enzyme catalyses the following chemical reaction
The synthesis of (S)-ò-macrocarpene from (2E,6E)-farnesyl diphosphate proceeds in two steps.