(âÂÂ)-ñ-Cuprenene synthase (EC 4.2.3.95, Cop6) is an enzyme with systematic name (âÂÂ)-ñ -cuprenene hydrolase (cyclizing, (âÂÂ)-ñ-cuprenene-forming). This enzyme catalyses the following chemical reaction
The enzyme from the fungus Coprinopsis cinerea produces (âÂÂ)-ñ-cuprenene with high selectivity.