(+)-epi-ñ-Bisabolol synthase (EC 4.2.3.138) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-epi-ñ-bisabolol-forming). This enzyme catalyses the following chemical reaction:
This enzyme is isolated from the plant Phyla dulcis (Aztec sweet herb).