(+)-ò-Pinene synthase (EC 4.2.3.122, (+)-pinene cyclase, cyclase III) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase [(+)-ò-pinene-forming]. This enzyme catalyses the following chemical reaction
Cyclase III from Salvia officinalis (sage) gives roughly equal parts of (+)-ò-pinene and (+)-ñ-pinene.